Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY |
| Enrichment Score (ES) | -0.82112896 |
| Normalized Enrichment Score (NES) | -1.6774528 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.012812135 |
| FWER p-Value | 0.162 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HRAS | 4868 | 2610 | 0.906 | -0.1262 | No | ||
| 2 | CDK5R1 | 20745 | 3007 | 0.553 | -0.1389 | No | ||
| 3 | MAP2K5 | 19088 | 3237 | 0.426 | -0.1446 | No | ||
| 4 | SRF | 22961 1597 | 3826 | 0.245 | -0.1724 | No | ||
| 5 | RIT2 | 5380 | 5796 | 0.073 | -0.2772 | No | ||
| 6 | RAP1A | 8467 | 6027 | 0.066 | -0.2885 | No | ||
| 7 | NTF3 | 16991 | 6527 | 0.053 | -0.3145 | No | ||
| 8 | NRAS | 5191 | 6779 | 0.047 | -0.3273 | No | ||
| 9 | RPS6KA1 | 15725 | 10766 | -0.011 | -0.5416 | No | ||
| 10 | RPS6KA5 | 2076 21005 | 13512 | -0.073 | -0.6882 | No | ||
| 11 | CREB1 | 3990 8782 4558 4093 | 14365 | -0.137 | -0.7318 | No | ||
| 12 | FOS | 21202 | 14800 | -0.201 | -0.7521 | No | ||
| 13 | RUSC1 | 1853 15283 | 14848 | -0.209 | -0.7513 | No | ||
| 14 | MAPK7 | 1381 20414 | 15238 | -0.299 | -0.7676 | No | ||
| 15 | MAP2K1 | 19082 | 15318 | -0.325 | -0.7667 | No | ||
| 16 | MAP3K2 | 11165 | 15532 | -0.412 | -0.7717 | No | ||
| 17 | MEF2C | 3204 9378 | 16221 | -0.946 | -0.7940 | No | ||
| 18 | CDK5 | 16591 | 16727 | -1.545 | -0.7969 | Yes | ||
| 19 | MAP2K3 | 20856 | 16736 | -1.563 | -0.7729 | Yes | ||
| 20 | MAPK3 | 6458 11170 | 16931 | -1.809 | -0.7550 | Yes | ||
| 21 | MAP2K6 | 20614 1414 | 17087 | -2.043 | -0.7314 | Yes | ||
| 22 | RAF1 | 17035 | 17131 | -2.125 | -0.7005 | Yes | ||
| 23 | PRKCD | 21897 | 17290 | -2.395 | -0.6715 | Yes | ||
| 24 | MAPK14 | 23313 | 17421 | -2.682 | -0.6365 | Yes | ||
| 25 | RAP1B | 10083 | 17703 | -3.362 | -0.5990 | Yes | ||
| 26 | RIT1 | 5382 | 18207 | -5.057 | -0.5469 | Yes | ||
| 27 | EHD4 | 8275 | 18351 | -5.835 | -0.4633 | Yes | ||
| 28 | KRAS | 9247 | 18396 | -6.150 | -0.3695 | Yes | ||
| 29 | MAPKAPK2 | 13838 | 18416 | -6.306 | -0.2718 | Yes | ||
| 30 | EGR1 | 23598 | 18587 | -8.944 | -0.1410 | Yes | ||
| 31 | MAPK1 | 1642 11167 | 18592 | -9.104 | 0.0013 | Yes |
